The Presence of Taxol and Related Compounds in Taxus Baccata Native to the Ukraine (Crimea), Georgia, and Southern Russia

نویسندگان

  • Thomas S. Elias
  • Ana Botanic Garden
  • Vladislav V. Korzhenevsky
چکیده

Twenty-eight leaf and twig samples and one bark sample of Taxus baccata from the Ukraine (Crimea), Russia, and Georgia were analyzed for taxane compounds. Taxol and the related diterpenoid I 0-deacetylbaccatin III (baccatin Ill) were present in all samples and 20.7% of those samples exhibited a taxol content nearly equal to or greater than that obtained from the bark of the Pacific Yew, T. brevifolia. Taxus baccata is a potential significant source of taxol, the most promising new drug identified in the last twenty years for the treatment of selected forms of cancer.

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تاریخ انتشار 2017